. Author manuscript; available in PMC: 2009 Dec 1.

Published in final edited form as: Clin Cancer Res. 2008 Dec 1;14(23):7956–7962. doi: 10.1158/1078-0432.CCR-08-1199

Table 5.

Joint Effects of Unfavorable Genotypes in Case and Control Subjects in Caucasinas

Risk group (No. unfavorable genotypes)	Case	Control	OR (95% CI)^*	P value
Low risk reference group (n= 0–1)	43	76	Reference
Medium risk group (n= 2)	83	93	1.55 (0.96–2.50)	0.075
High risk group (n= 3–5)	150	108	2.49 (1.58–3.91)	<0.001
P for trend				<0.001

Adjusted for age, gender, and smoking status.

^†

Unfavorable genotype: DICER1 (rs3742330): AA, AGO1 (rs595961): AA, GEMIN4 (rs2740330): GG, GEMIN4 (rs7813): TT, GEMIN3 (rs197412): TC+CC, GEMIN3 (rs197388) : TA+AA