TABLE 2.
Outcomea | Value for patients (n = 275)f grouped according to:
|
P valuee | ||
---|---|---|---|---|
Low MICb (n = 56) | Intermediate MICc (n = 201) | High MICd (n = 18) | ||
Mortalityf | 8 (12.5%) | 26 (11.5%) | 3 (14.3%) | 0.91g |
Length of stay postculture (days) | 7.3 (6.8) | 7.9 (8.8) | 16.4 (20.6)h | 0.02 |
Length of levofloxacin treatment postculture (days) | 4.8 (4.7) | 6.2 (6.2) | 13.3 (17.4)i | 0.01 |
Duration of infection (days) | 1.0 (0.1) | 1.2 (0.8) | 2.1 (1.9)j | <0.001 |
All data are presented as the mean (standard deviation) unless otherwise indicated.
A low MIC was defined as a levofloxacin MIC of ≤0.25 mg/liter.
An intermediate MIC was defined as a levofloxacin MIC of 0.5 mg/liter.
A high MIC was defined as a levofloxacin MIC of 1 or 2 mg/liter.
Determined by the Kruskal-Wallis test unless otherwise indicated.
The total number of patients including those who died was 312; patients who died were not considered in analyses of outcomes other than mortality.
Determined by a χ2 test.
Results of Mann-Whitney U nonparametric test for two groups, the high-MIC group versus all others: P = 0.006.
Results of Mann-Whitney U nonparametric test for two groups, the high-MIC group versus all others: P = 0.02.
Results of Mann-Whitney U nonparametric test for two groups, the high-MIC group versus all others: P < 0.001.