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. 2008 Dec 15;53(3):1074–1079. doi: 10.1128/AAC.00580-08

TABLE 2.

Comparisons of lengths of stay and treatment outcomes for surviving patients with bloodstream infections caused by gram-negative organisms in the low-, intermediate-, and high-MIC groups

Outcomea Value for patients (n = 275)f grouped according to:
P valuee
Low MICb (n = 56) Intermediate MICc (n = 201) High MICd (n = 18)
Mortalityf 8 (12.5%) 26 (11.5%) 3 (14.3%) 0.91g
Length of stay postculture (days) 7.3 (6.8) 7.9 (8.8) 16.4 (20.6)h 0.02
Length of levofloxacin treatment postculture (days) 4.8 (4.7) 6.2 (6.2) 13.3 (17.4)i 0.01
Duration of infection (days) 1.0 (0.1) 1.2 (0.8) 2.1 (1.9)j <0.001
a

All data are presented as the mean (standard deviation) unless otherwise indicated.

b

A low MIC was defined as a levofloxacin MIC of ≤0.25 mg/liter.

c

An intermediate MIC was defined as a levofloxacin MIC of 0.5 mg/liter.

d

A high MIC was defined as a levofloxacin MIC of 1 or 2 mg/liter.

e

Determined by the Kruskal-Wallis test unless otherwise indicated.

f

The total number of patients including those who died was 312; patients who died were not considered in analyses of outcomes other than mortality.

g

Determined by a χ2 test.

h

Results of Mann-Whitney U nonparametric test for two groups, the high-MIC group versus all others: P = 0.006.

i

Results of Mann-Whitney U nonparametric test for two groups, the high-MIC group versus all others: P = 0.02.

j

Results of Mann-Whitney U nonparametric test for two groups, the high-MIC group versus all others: P < 0.001.