FIG. 5.

Antiviral activities of the gB94, gB122, and gB131 peptides. (A) To test for entry inhibition, virus was attached to cells at 4°C, peptide was added, and the cultures were shifted to 37°C. (B) To test for cell protection, Vero cells were incubated with various concentrations of peptide for 1 h at 37°C, rinsed, and then infected with hrR3. (C) To test for virucidal activity, peptide was incubated with virus for 1 h at 37°C and serially diluted, and then the titers were determined on Vero cells. For all studies, β-galactosidase (β-gal) activity was determined at 6 h postinfection as a measure of infectivity. The graph is a representative result from at least two independent experiments. Each point and error bar represents the mean ± standard deviation of triplicate samples.