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. 2008 Dec 22;53(3):987–996. doi: 10.1128/AAC.00793-08

TABLE 1.

Sequences of the seven inhibitory peptides, locations in gB-1, and EC50sa

Peptideb Sequence gB location (amino acid residues) Domainc EC50 (μM)d
gB64 TTPKFTVAWDWVPKR 346-360 I 85
gB82 VGQPQYYLANGGFLI 436-450 II NDe
gB94 KTTSSIEFARLQFTY 496-510 III 6.5
gB95 IEFARLQFTYNHIQR 501-515 III ND
gB110 VAADNVIVQNSMRIS 576-590 IV ND
gB122 GHRRYFTFGGGYVYF 636-650 IV 15
gB131 HEVVPLEVYTRHEIK 681-695 V 18
a

At least one peptide maps to each of the five subdomains of gB-1.

b

The peptides are designated sequentially starting at residue 30 of mature gB-1 and extending to the start site of the transmembrane segment.

c

The domain nomenclature is that of Heldwein et al. (36).

d

Comprehensive assay.

e

ND, not determined due to poor solubility.