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Comparison of mean caspofungin plasma concentrations in neonates and infants (25 mg/m2; n = 18 on day 1 and n = 11 or 12 on day 4) to mean caspofungin plasma concentrations in adults (50 mg/day; n = 6), young children (3 to 24 months) (50 mg/m2; n = 6 on day 1 and n = 7 on day 4), older children (2 to 11 years) (50 mg/m2; n = 8), and adolescents (12 to 17 years) (50 mg/m2; n = 10).
