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. 2008 Dec 22;53(3):1067–1073. doi: 10.1128/AAC.00860-08

TABLE 3.

Maternal minimal and maximal concentrations (Cmin and Cmax) and AUCs derived from women's individual pharmacokinetic estimates, after a 400-mg FTC dose was administered to each of the HIV-infected pregnant women (n = 38) enrolled in the TEmAA ANRS 12109 trial, step 1, compared to median values for other adults after a 200-mg FTC dose at steady state

Study (reference) Median (range)
AUC (mg/liter·h) Cmin (mg/liter) Cmax (mg/liter)
TEmAA 14.3 (11.0-19.0) 0.076 (0.039-0.174) 1.68 (0.82-2.13)
Zhong et al. study (18) 10.7 0.071 2.18
Blum et al. study (4) 10.7 0.075 1.69
Ramanathan et al. study (15) 9.8 0.085 1.68