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. 2009 Jan 5;53(3):863–868. doi: 10.1128/AAC.00899-08

TABLE 2.

Steady-state pharmacokinetics of EFV with and without RMPa

Treatment Cmax Cmin Tmax AUC(0-24) CL t1/2
EFV 9.88 ± 9.38 5.84 ± 7.54 2.53 ± 1.07 169.77 ± 205.34 7.25 ± 5.10 24.98 ± 13.19
EFV + RMP 8.12 ± 7.10 4.65 ± 5.80 2.47 ± 0.97 138.19 ± 148.28 9.27 ± 6.52 17.57 ± 9.42b
a

The values shown are means ± standard deviations for 19 patients. Tmax, time to attain Cmax; t1/2, half-life.

b

P < 0.05.