TABLE 2.
Clonal analysis results for the three virologic failure subjects with tropism readout changesa
| Subject | Visit | Population tropism | No. of clones confirmed with indicated tropism
|
||
|---|---|---|---|---|---|
| R5 | R5X4 | X4 | |||
| P3 | Screening | R5 | NT | NT | NT |
| Day 1 | R5 | 12 | 0 | 0 | |
| Week 4 | NP | NT | NT | NT | |
| Week 8 | NT (HIV RNA < 1,000 c/ml) | NT | NT | NT | |
| Week 12 | DM | NT | NT | NT | |
| Week 16 (VF) | DM | 8 | 4 | 0 | |
| P5 | Screening | R5 | 11 | 1 | 0 |
| Day 1 | R5 | 12 | 0 | 0 | |
| Week 2 | DM | NT | NT | NT | |
| Week 4 | R5 | 12 | 0 | 0 | |
| Week 8 | DM | NT | NT | NT | |
| Week 12 (VF) | DM | 11 | 1 | 0 | |
| P8 | Screening | R5 | NT | NT | NT |
| Day 1 | DM | 7 | 5 | 0 | |
| Day 21 | DM | NT | NT | NT | |
| Week 4 (VF) | DM | 7 | 5 | 0 | |
a
NP, nonphenotypeable; NT, not tested; VF, virologic failure.