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(A) Schematic diagram of HIV-1 gp41 and sequences of C-HR-derived peptides. FP, fusion peptide; TM, transmembrane domain. The residues at each position in the helical turns are denoted in italics. *Z, an artificial amino acid, norleucine, instead of methionine, to avoid oxidation of the side chain of methionine; †, possible electrostatic interactions indicated by lines and correlating amino acids. (B) One heptad helical turn.
