Table 1.
Clinical response rates (percent cured and improved) for azithromycin (5-day formulation) versus various comparator(s) at early and late time points
Study | Year | Comparator | Azithromycin 5-day formulation
|
Various comparators
|
Definition of chronic bronchitis | ||
---|---|---|---|---|---|---|---|
Early | Late | Early | Late | ||||
Dark | 1993 | Cefaclor | 100.0 | NS | 92.0 | NS | NS |
Whitlock | 1995 | Amoxicillin-clavulanate | 100 | 90.0 | 93.0 | 85.0 | ATS |
DeAbate et al | 2000 | Moxifloxacin | 92.0 | 88.0 | 91.0 | 88.0 | ATS |
Amsden et al | 2003 | Levofloxacin | 88.9 | 81.9 | 92.4 | 85.6 | ATS |
Castaldo et al | 2003 | Dirithromycin | 75.7 | 86.5 | 84.8 | 95.5 | ATS |
Abbreviations: ATS, American Thoracic Society; NS, not stated.