Figure 4.

Consensus sequence upstream of class I late genes. (A) Multiple alignment of upstream sequences of hctB, ltuB, CPj0332, and adk genes. They have a consensus sequence partially similar to σ²⁸ promoter consensus sequence. (B). Multiple alignment of upstream sequences of CPj0331, CPj0678, omcA, and hctA genes of C. pneumoniae and the ortholog genes in C. trachomatis (CT). CT082 is the ortholgog of CPj0331. Number represents nucleotides from the putative translation initiation site. Consensus sequences are determined as three or more of four nucleotides are identical in C. pneumoniae genes, or two or more are identical in C. trachomatis. Asterisks represent conserved nucleotides in all genes in each species. Highly conserved regions in C. pneumoniae genes are boxed with dashed lines. Sequence logos are generated with WebLogo (http://weblogo.berkeley.edu/) using aligned sequences of C. pneumoniae genes.