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. 2009 Feb 10;5:5. doi: 10.1186/1744-8069-5-5

Figure 1.

Figure 1

TRPV1 and TRPV4 are co-localized in dorsal root ganglion (DRG) neurons. A. Immunostaining of TRPV1 in DRG. B. Immunostaining of TRPV4 in DRG. C. Merged images of A and B. D. Expanded merged image. Bar = 50 μm. E. Summary graph showing the expression of TRPV1, TRPV4 and the extent of co-expression (n = 4). F. Ca2+ fluorescence imaging showing capsaicin- and 4α-PDD-induced responses in the same neurons. G. Whole-cell current trace showing capsaicin- and 4α-PDD-mediated current responses in the same neuron.