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. Author manuscript; available in PMC: 2009 Mar 4.
Published in final edited form as: Int J Epidemiol. 2008 Feb 8;37(2):301–308. doi: 10.1093/ije/dyn002

Table 4.

Estimated systolic blood pressure (SBP) in mmHg at age 3 years in children of mothers with and without anemia or low iron intake in the 1st or 2nd trimester of pregnancy

Mean (SE) SBP Mean (SE) SBP Difference (mmHg) 95% Confidence Interval P-value
Anemia No Yes
        1st Trimester 97.5 (3.4) 99.1 (3.0) −1.6 −5.0, 1.8 0.36
        2nd Trimester 97.3 (3.4) 97.0 (3.6) 0.3 −1.7, 2.3 0.76
Low iron intake No Yes
        1st Trimester 97.4 (3.0) 96.8 (3.0) 0.5 −0.6, 1.7 0.36
        2nd Trimester 95.1 (3.1) 95.7 (3.1) −0.6 −2.3, 1.1 0.50

Anaemia in pregnancy is defined according to criteria published by the Centers for Disease Control and Prevention26 as haemoglobin level <11 g/dl in the first trimester and <10.5 g/dl in the second trimester. Low iron intake is defined as <27 mg/day, the Recommended Dietary Allowance during pregnancy.25 Estimates are adjusted for blood pressure measurement conditions (extremity used, cuff size, state, position, measurement order), child gestational age, sex and age, height and weight at the time of blood pressure measurement; and for maternal age, pre-pregnancy body mass index, pregnancy weight gain, smoking, income, education and race/ethnicity. SE is standard error.