TABLE 5.
Correlation of IFN-γ release detected by QFT-G and ICC assays with lymphocyte subsets from the TB groupa
| Cell type | IFN-γ concn (IU/ml) determined by QFT-G assay (P value) | % IFN-γ+ CD4+ T cells determined by ICC assay (P value) |
|---|---|---|
| Lymphocytes | 0.095 (NSb) | 0.065 (NS) |
| CD3+ cells | 0.066 (NS) | −0.002 (NS) |
| CD3+ CD4+ cells | 0.570 (<0.05) | 0.135 (NS) |
| CD3+ CD8+ cells | −0.283 (NS) | −0.091 (NS) |
| NK cell (CD3-CD16+ CD56+) | −0.010 (NS) | −0.038 (NS) |
| B cell (CD3- CD19+) | 0.18 (NS) | 0.298 (NS) |
a
n = 17 for the TB group.
b
NS, not statistically significant.