TABLE 3.
Overall summary results of estimates, with 95% confidence limits, for samples A to D (IgA) in terms of units of U.S. lot 5a
| Antibody and assay | Estimates as units of U.S. reference lot 5 under sample code:
|
Estimates for B and C as equivalent ml of A and D | Estimates for B and C in terms of Ab | Proposed IU for A and D (06/140 and 06/146) | |||
|---|---|---|---|---|---|---|---|
| A (06/140) | D (06/146) | B (06/142) | C (06/144) | ||||
| IgA anti-PT ELISA | 63.0 (49.8-79.7) [8] | 62.4 (48.8-77.1) [8] | 20.4 (13.5-30.9) [8] | 20.1 (13.1-30.8) [8] | 0.32 (0.22-0.48) [8] | 21.1 (14.3-30.9) [8] | NAc |
| IgA anti-PT (omit lab 21) | 65.3 (50.3-84.8) [7] | 63.8 (49.7-81.9) [7] | 18.4 (12.4-27.3) [7] | 18.2 (11.9-27.9) [7] | 0.28 (0.22-0.35) [7] | 18.3 (14.5-23.1) [7] | 65 |
| IgA anti-FHA ELISA | 70.5 (54.5-91.3) [8] | 68.0 (53.8-85.8) [8] | 90.7 (74.3-110.8) [8] | 87.6 (73.3-104.8) [8] | 1.30 (1.21-1.39) [8] | 84.2 (78.5-90.4) [8] | NA |
| IgA anti-FHA (omit lab 21) | 65.7 (52.0-83.0) [7] | 63.3 (52.3-76.5) [7] | 86.7 (70.9-105.9) [7] | 83.3 (71.0-97.7) [7] | 1.33 (1.26-1.39) [7] | 86.3 (82.2-90.6) [7] | 65 |
| IgA anti-PRN ELISA | 42.8 (34.6-52.9) [5] | 41.9 (37.1-47.5) [5] | 37.5 (33.6-41.8) [5] | 38.5 (33.8-43.7) [5] | 0.90 (0.76-1.06) [5] | 37.6 (31.9-44.3) [5] | 42 |
a
The 95% confidence limits are given in parentheses. The numbers of estimates (one estimate per laboratory) combined are indicated in brackets.
b
Using proposed IU for sample A.
c
NA, not applicable.