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. 2009 Jan 21;16(3):387–396. doi: 10.1128/CVI.00415-08

TABLE 5.

Dilution effect estimates and accompanying tests of statistical significancea

Serotype Panel 1:1,000 to 1:10,000
1:10,000 to 1:100,000
No. of subjects Dilution effectb (%) 95% CI (%) Paired t test P value No. of subjects Dilution effect (%) 95% CI (%) Paired t test P value
3 B 3 14.2 3.6, 25.8 0.028 19 1.3 −10.1, 14.3 0.820
D 9 −17.8 −32.9, 0.7 0.056
4 B 8 8.9 −4.1, 23.7 0.158 22 −3.5 −12.0, 5.9 0.436
D 6 −6.7 −26.3, 18.3 0.488 6 −2.9 −11.6, 6.7 0.461
6B B 15 4.3 −3.7, 13.0 0.280 15 3.0 −3.1, 9.5 0.316
D 6 −3.6 −23.6, 21.7 0.706
9V B 9 5.2 −3.8, 14.9 0.226 20 −3.5 −13.1, 7.2 0.488
D 8 3.6 −9.1, 18.1 0.540 5 −17.8 −42.4, 17.3 0.200
14 B 15 7.7 2.5, 13.2 0.006 18 2.7 −3.9, 9.9 0.408
D 10 −1.7 −11.4, 9.0 0.716 2 −26.2 −90.5, 470.8 0.310
18C B 4 12.2 −6.0, 34.0 0.131 23 9.3 2.7, 16.4 0.007
D 11 9.3 −5.7, 26.7 0.211 7 −4.1 −15.4, 8.8 0.452
19F B 16 13.6 6.4, 21.2 <0.001 21 1.8 −6.1, 10.4 0.646
D 10 2.9 −16.0, 26.2 0.756 3 −6.4 −34.8, 34.5 0.517
23F B 13 10.5 3.9, 17.5 0.004 18 2.0 −9.0, 14.3 0.719
D 9 −8.6 −16.8, 0.4 0.059
a

Panels B (adults) and D (pediatrics) are described in Table 1. 95% CI, 95% confidence interval.

b

Dilution effects describe the effect per 10-fold dilution.