TABLE 5.

Detection of anthrax PA in mice infected with B. anthracis spores by ENIA^a

Dosage (no. of spores/mouse)	Bleed time (h)	No. of animals	Illness grade	PA concn in blood (ng/ml)
103	24-237	13	−	0.00
107	6	2	−	0.00
107	8	2	−	0.00
107	24	2	+b	68 ± 75
107	42-48	2	+++	408 ± 275
0	24	2	−	0.00

^aDBA/2J mice were exposed to different doses of B. anthracis spores and were bled at different times after infection. PA levels in plasma were assessed by ENIA. The samples were diluted from 1:10 to 1:1,000.

^bEdema.