TABLE 3.
Detection with five primer pairs of H. pylori in saliva and gastric samples
| Parametera | Primer pair and sample typeb
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Hp1/HP2
|
HP64-f/HP64-r
|
VAG-F/VAG-R
|
EHC-U/EHC-L
|
ICT37/ICT38
|
||||||
| G | S | G | S | G | S | G | S | G | S | |
| True positive (n) | 16 | 4 | 15 | 4 | 15 | 5 | 8 | 3 | 11 | 4 |
| False negative (n) | 1 | 13 | 2 | 13 | 2 | 12 | 9 | 14 | 6 | 13 |
| False positive (n) | 4 | 5 | 4 | 1 | 4 | 4 | 1 | 0 | 0 | 3 |
| True negative (n) | 16 | 15 | 16 | 19 | 16 | 16 | 19 | 20 | 20 | 17 |
| Sensitivity (%) | 94 | 24 | 88 | 24* | 88 | 29 | 47 | 18 | 65 | 24 |
| Specificity (%) | 80 | 75 | 80 | 95 | 80 | 80 | 95 | 100 | 100 | 85 |
| PPV (%) | 80 | 44 | 79 | 80 | 79 | 56 | 89 | 100 | 100 | 57 |
a
n, Number of samples; PPV, positive predictive value.
b
G, gastric biopsy sample; S, saliva sample. *, The sensitivity is provided but is not an representative in this case because the finding of H. pylori is dependent on whether it refluxed from the stomach and thus is a random event.