TABLE 4.
Mutation patterns of QRDRs by phylogroup and PAIusp subtypea
| Phylogroup | PAIusp subtype | No. of FQREC isolates
|
No. of FQSEC isolates
|
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | CarryinggyrA(S83L D87N) and parC(S80I) with:
|
With other pattern | |||||||||
| No mutation | parC(E84V) | parC(E84G) | parE(S458A) | Total | With no mutation | WithgyrA(S83L) | With other pattern | ||||
| A | None | 5 | 4 | 1 | 5 | 5 | |||||
| B1 | None | 9 | 3 | 1 | 5 | 4 | 3 | 1 | |||
| B2 | 1a | 2 | 1 | 1 | 17 | 12 | 5 | ||||
| 1b | 0 | 8 | 6 | 1 | 1 | ||||||
| 2a | 36 | 3 | 30 | 3 | 29 | 27 | 1 | 1 | |||
| 2b | 5 | 5 | 13 | 12 | 1 | ||||||
| NTb | 0 | 2 | 2 | ||||||||
| None | 1 | 1 | 0 | ||||||||
| D | 1a | 0 | 4 | 4 | |||||||
| 2a | 5 | 2 | 1 | 2 | 0 | ||||||
| None | 26 | 13 | 1 | 4 | 3 | 5 | 7 | 6 | 1 | ||
a
Eighty-nine FQREC isolates and 89 FQSEC isolates were used.
b
NT, nontypeable.