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. Author manuscript; available in PMC: 2009 Nov 27.
Published in final edited form as: J Med Chem. 2008 Nov 27;51(22):7205–7215. doi: 10.1021/jm800825n

Figure 3.

Figure 3

Figure 3

Figure 3

STD NMR results for compounds tested for binding to hTR-P2b RNA. The first number simply refers to its number in this table, which is used in the text for identification, and the second number is the compound identification number in the ZINC database; “+” signifies that the compound shows a distinct preference for binding to hTR-P2b RNA relative to A-site rRNA as assessed by STD NMR; “++” signifies that the compound shows no indication of binding to A-site rRNA but binds hTRP2b RNA; “=” indicates binding is comparable to the two RNA species, and “-“ indicates a preference for binding to the A-site rRNA transcript. Colors indicate STD NMR spectral intensities, which roughly correlate with binding affinity: weak (yellow), medium (green), strong (blue) or no STD effect observed (white).