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. 2009 Jan 20;27(3):365–370. doi: 10.1200/JCO.2008.17.9184

Table 1.

Characteristics of Patients With INSS Stage 1 or 2 Neuroblastoma and MYCNAmplification (N = 87)

Characteristic Total
5-Year EFS
5-Year OS
No. % % SE P % SE P
Overall patients 87 53 8 72 7
INSS stage
    1 48 55 50 12 .2760 76 9 .3568
    2a/2b 39 45 57 12 67 11
Histology
    Favorable 32 56 58 15 .2029 86 9 .1065
    Unfavorable 25 44 40 18 62 19
    Unknown 30
Ploidy
    Hyperdiploid 17 44 82 20 .0069 94 11 .0056
    Diploid 22 56 37 21 54 15
    Unknown 48
1p
    No loss or aberration 11 44 73 27 .4177 73 27 .4197
    LOH or aberration 14 56 56 17 85 12
    Unknown 62
LDH, U/L
    < 580 32 51 63 12 .3522 83 9 .0883
    ≥ 580 31 49 48 14 62 14
    Unknown 24
Age, days
    < 547 54 62 58 10 .4320 77 8 .1798
    ≥ 547 33 38 45 14 63 14

Abbreviations: INSS, International Neuroblastoma Staging System; EFS, event-free survival; OS, overall survival; LOH, loss of heterozygosity; LDH, lactate dehydrogenase.