Table 2.
Outcomes of Patients With Low-Stage, MYCN-Amplified Neuroblastoma Based on Initial Post-Surgical Therapy
| Treatment | Total
|
5-Year EFS
|
5-Year OS
|
|||||
|---|---|---|---|---|---|---|---|---|
| No. | % | % | SE | P | % | SE | P | |
| Surgery alone | 29 | 40 | 50 | 16 | .2938* | 81 | 11 | .5115* |
| Moderate intensity chemotherapy (2-8 cycles) plus surgery | 22 | 30 | 50 | 14 | 64 | 13 | ||
| Intensive chemotherapy + radiotherapy | ||||||||
| Specific type unknown | 6 | 8 | 50 | 25 | 67 | 22 | ||
| No stem cell or bone marrow transplant | 7 | 10 | 71 | 22 | 71 | 22 | ||
| Plus stem cell or bone marrow transplant | 9 | 12 | 50 | 25 | 62 | 27 | ||
| Unknown | 14 | |||||||
Abbreviations: EFS, event-free survival; OS, overall survival.
*
Comparison of surgery alone or surgery plus moderate intensity chemotherapy v surgery plus intensive chemotherapy plus radiotherapy with or without transplant.