Table A3.
Ovarian Tumor Characteristics
| Sequence Change | Sample | Race | Conserved Domain | LOH | A-GVGD Class | In Trans | Stage | Grade | Age at Diagnosis (years) | Histology |
|---|---|---|---|---|---|---|---|---|---|---|
| BRCA1 truncating | ||||||||||
| 1135insA | 24127 | White | NA | WT | NA | No | ND | 3C | 59 | Papillary serous |
| 262delT | 0690 | White | NA | WT | NA | No | ND | 3C | 63 | Endometrioid |
| 3600del11 | 10945 | White | NA | WT | NA | No | ND | 3 | 41 | Serous |
| BRCA1 missense | ||||||||||
| P334L | 6167 | White | No | WT | C0 | Yes | ND | ND | 39 | Unspecified |
| BRCA2 truncating | ||||||||||
| 6307insA | 4945 | Af Am | NA | None | NA | NA | ND | ND | ND | Unspecified |
| 7297delCT | 0947 | White | NA | None | NA | NA | ND | 3C | 22 | Serous |
| 7990del3ins2 | 540 | White | NA | None | NA | NA | ND | ND | 46 | Unspecified |
| 9481insA | 23722 | White | NA | WT | NA | NA | ND | 3C | 59 | Papillary serous |
| BRCA2 missense | ||||||||||
| A1170V | 97594 | White | No | V | C0 | No | ND | ND | 59 | ND |
| D1420Y | 0690 | White | No | None | C15 | Yes | ND | 3C | 63 | Endometrioid |
| L2721H | 6167 | White | Yes | WT | C25 | No | ND | ND | 39 | Unspecified |
| M784V | 11073 | Asian | No | V | C0 | No | IIIC | 3 | 45 | Unspecified |
| S1172L | 5701 | White | No | None | C15 | No | IIIC | ND | 58 | Serous |
| S326R | 5701 | White | No | None | C0 | Yes | IIIC | ND | 58 | Serous |
| V1643A | 76,049 | White | No | WT | C0 | No | IIIC | ND | 50 | Serous |
Abbreviations: LOH, loss of heterozygosity; A-GVGD, align grantham variation, grantham deviation; NA, not applicable; WT, loss of wild-type allele; ND, no data; Af Am, African American; V, loss of variant or mutant allele.