. Author manuscript; available in PMC: 2010 Jan 15.

Published in final edited form as: Bioorg Med Chem Lett. 2008 Nov 20;19(2):418–423. doi: 10.1016/j.bmcl.2008.11.054

Table 2.

IC₅₀ values of FMN against enzyme targets^a

Enzyme	C. hominis TS-DHFR	Human DHFR	Human TS	T. gondii TS-DHFR
IC₅₀ (μM)	55 ± 7	325 ± 50	>500	>500

All reactions were run with identical enzyme and ligand concentrations. Values are the averages of at least three independent experiments.