Fig. 1.
Direct contact transmissibility of wild-type, mutant, and reassortant avian H1N1 viruses. We inoculated 3 ferrets with 106 EID50 of Dk/NY/96 (A), Dk/NY/96-DD (B), 1918NA:Dk/NY/96-DD (C), or 1918HANA:Dk/NY/96 (D). One day p.i., a naive ferret was placed in each cage to establish contact between the animal pairs. Viral replication was monitored by titration of NWs collected every other day in both inoculated (Left) and contact (Right) animals. The limit of detection was 101.5 EID50/mL, and is indicated by a solid line on each representation.