Table 1.
Strain, clone | Description | Dose | No. of cultures positive/total no. of specimens examined |
No. of mice infected/total no. of mice | |||
---|---|---|---|---|---|---|---|
Heart | Joint | Skin | All sites | ||||
297 | WT B. burgdorferi | 104 | 7/7 | 7/7 | 7/7 | 21/21 | 7/7 |
OY04/D4 | 297, ΔbmtA* | 104 | 0/6 | 0/6 | 0/6 | 0/18 | 0/6 |
OY04/F42 | 297, ΔbmtA | 104 | 0/6 | 0/6 | 0/6 | 0/18 | 0/6 |
OY04/D4 | 297, ΔbmtA | 107 | 0/5 | 0/5 | 0/5 | 0/15 | 0/5 |
OY04/F42 | 297, ΔbmtA | 107 | 0/5 | 0/5 | 0/5 | 0/15 | 0/5 |
OY06/F6 | OY04/D4 transformed with pOY15 | 104 | 3/3 | 3/3 | 3/3 | 9/9 | 3/3 |
OY06/D11 | OY04/F42 transformed with pOY15 | 104 | 3/3 | 3/3 | 3/3 | 9/9 | 3/3 |
OY07/F1 | OY04/D4 transformed with pJD54 | 104 | 0/3 | 0/3 | 0/3 | 0/9 | 0/3 |
OY07/F62 | OY04/F42 transformed with pJD54 | 104 | 0/3 | 0/3 | 0/3 | 0/9 | 0/3 |
OY07/F1 | OY04/D4 transformed with pJD54 | 107 | 0/3 | 0/3 | 0/3 | 0/9 | 0/3 |
OY07/F62 | OY04/F42 transformed with pJD54 | 107 | 0/3 | 0/3 | 0/3 | 0/9 | 0/3 |
*ΔbmtA: bmtA mutant.