Fig. 4.
Messenger RNA levels in kidney tissue in relation to TLR4 mutation and kidney function. (A) Gene expression in relation to the TLR4-donor genotype (WT n = 38; TLR4 mutated n = 10). (B) Expression levels of tubular injury marker IL-18, TNFα, MCP-1, T-cell marker (CD3ε), and HO-1 were analyzed in kidneys with IGF (n = 22) or DGF (n = 26). Box and whisker blots show the medians, and the percentile values (10, 25, 75, 90) for normalized mRNA.