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(a) Percentage of myocardial DNA laddering, an index of apoptosis, obtained at 7 and 14 weeks of age in lean (+/+) and obese (fa/fa) ZDF rats (*, P < 0.01). (b) Myocardial ceramide levels in lean (+/+) and obese (fa/fa) ZDF rats at 7 and 14 weeks of age (*, P < 0.01). (c) Myocardial iNOS mRNA in lean (+/+) and obese (fa/fa) ZDF rats at 7 and 14 weeks of age.
