Figure 3.

Restoration of the elicitation phase of the contact-hypersensitivity response to nickel sulfate in UVB-irradiated human skin through photoreactivation. Histological pictures (×100) of patch test reactions to nickel sulfate in human skin. Skin areas had been left unirradiated (a); UVB-irradiated (2 MED) before patch testing (b); or UVB-irradiated, then topically treated with photolyase-containing liposomes, followed by exposure to photoreactivating light before patch testing (c). Biopsies were taken 48 h after application of the patch test.