Fig. 1.

False positive FDG PET/CT caused by breast silicone injection in 40-year-old female.

A-C. Transverse slices of one hour post-injection ¹⁸F-FDG PET scan (A), CT (B) and PET/CT fusion image (C) showed focal area of increased ¹⁸F-FDG uptake (arrows; maximal SUV = 3.7) in left breast anterolateral to saline bag.

D. Delayed ¹⁸F-FDG PET imaging at two hour post-injection showed further increase of ¹⁸F-FDG uptake in above lesion (arrow; maximal SUV = 4.8).

E. Foreign body reaction to silicone (siliconoma). Variable-sized silicone spaces were surrounded by multinucleated foreign body-type giant cells, some foamy macrophages and some lymphocytes.