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. Author manuscript; available in PMC: 2009 Jul 15.
Published in final edited form as: Nature. 2008 Nov 23;457(7227):336–339. doi: 10.1038/nature07512

Fig. 3.

Fig. 3

Replication-loop dynamics depend on primase activity. Loop growth and lag times are compared for different concentrations of ribonucleotides. Replication-loop lengths and lag times were determined as described in Figure 1. For loop lengths, sample size n=288 at 300 µM ATP, 300 µM CTP; n=61 at 30 µM ATP, 10 µM CTP; and n=72 at 30 µM ATP, 10 µM CTP, 300 µM pAC. For lag times, n=135 at 300 µM ATP, 300 µM CTP; n=25 at 30 µM ATP, 10 µM CTP; and n=30 at 30 µM ATP, 10 µM CTP, 300 µM pAC.