Table 1.
Gene name | Type of tyrosine kinase | Number of clones in Y1 cells | Number of clones in rat adrenal gland |
---|---|---|---|
IGF1-R | Receptor | 57 | 24 |
Jak 1 | Signaling molecule | 23 | 28 |
Ryk | Receptor | 9 | 0 |
Axl | Receptor | 11 | 2 |
FGF-R | Receptor | 2 | 3 |
Tyk2 | Signaling molecule | 3 | 31 |
Megakaryocyte associated tyrosine kinase | Signaling molecule | 2 | 0 |
c-abl | Signaling molecule | 3 | 2 |
Jak 3 | Signaling molecule | 2 | 6 |
SRC | Signaling molecule | 1 | 5 |
FER | Signaling molecule | 1 | 5 |
Jak 2 | Signaling molecule | 0 | 3 |
CSF-1 R | Receptor | 0 | 1 |
VEGF-R | Receptor | 0 | 1 |
HGF-R | Receptor | 0 | 1 |
v-ras | Signaling molecule | 0 | 1 |
Unknown | ? | 0 | 1 |
Total | 114 | 114 |
Summaries of the frequencies of tyrosine kinase domain cDNAs isolated from Y1 cells and normal rat adrenal gland. IGF1-R: insulin-like growth factor 1 receptor, FGF-R: fibroblast growth factor receptor, CSF-1R: colony stimulating factor 1 receptor, VEGF-R: vascular endothelial growth factor receptor, HGF-R: hepatocyte growth factor receptor.