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. Author manuscript; available in PMC: 2010 Jan 7.
Published in final edited form as: Vaccine. 2008 Nov 7;27(2):213–222. doi: 10.1016/j.vaccine.2008.10.046

Fig. 5.

Fig. 5

Booster immunogenicity study in horses, comparing rWNV-E candidate vaccine with the Fort Dodge Animal Health Innovator™ killed virus (FD) vaccine. Horses were immunized in prior years. Twenty horses were boosted with FD vaccine. Twenty horses were immunized with a single dose of rWNV-E vaccine intramuscularly with 50 μg of rWNV-E adsorbed to Alhydrogel™. Serum samples were collected (n=20 for the FD group; and n=19 for the rWNV-E boosted horses that responded after a single injection) throughout the study, and analyzed for IgG antibodies recognizing rWNV E-protein by ELISA (serum dilution 1:200) (A) and for neutralizing antibodies in a plaque reduction assay (PRNT50) (B). ELISA OD median values for each time course were calculated for each group.