TABLE 1.
Characteristics of the 12-Year-Old Cohort
| Preterm | Term | ||
|---|---|---|---|
| Brain injury |
No brain injury |
|
|
| Number of subjects at inception* | 58 | 408 | - |
| Proportion surviving to NICU discharge, No (%) | 42/58 (72%) | 398/408 (98%)+ | - |
| Proportion surviving to 12 years, No (%) | 39/58 (67%) | 395/408 (97%)+ | - |
| Follow-up at 12 years (%) | 34/39 (87%) | 337/395 (85%) | 111 |
| Child characteristics | |||
| Male sex, No (%) | 21 (62%) | 181 (54%) | 51 (46%) |
| Social factors | |||
| Maternal years at birth, mean (SD) | 27.5 (5.6) | 27.5 (6.1) | 29.3 (6.0) |
| Maternal years of education, mean (SD) | 13.8 (2.7) | 13.4 (2.3) | 14.3 (2.8) |
| Maternal education < High school, No (%) | 3/34 (9%) | 38/336 (11%) | 9/111 (8%) |
| Single parent household, No (%) | 11/34 (32%) | 115/332 (35%) | 31/111 (28%) |
| Minority status by maternal report, No (%) | 8/34 (24%) | 100/337 (30%) | 34/111 (31%) |
| Neurosensory impairment | |||
| Abnormal neurologic examination, No (%) | 17/34 (50%) | 23/337 (7%)+ | 0 |
| Cerebral palsy, No (%) | 17/34 (50%) | 17/337 (5%)+ | 0 |
| Ventriculo-peritoneal shunt, No (%) | 7/34 (21%) | 1/337 (0.3%)+ | 0 |
| Seizure disorder, No (%) | 6/33 (18%) | 5/327 (1.5%)+ | 0 |
| Hearing aids, No (%) | 4/33 (12%) | 8/323 (2.5%)+ | 0 |
| Blind services, No (%) | 5/32 (16%) | 4/325 (1.2%)+ | 0 |
| Any neurosensory impairment, No (%) | 21/34 (62%) | 34/333 (10%)+ | 0 |
| Glasses, No (%) | 15/33 (46%) | 109/327 (33%) | 33/111 (30%) |
| Mean age at assessment, mean (SD), years | 12.2 (0.4) | 12.2 (0.4) | 12.7 (0.8) |
*
Some children died or were discharged prior to near-term cranial ultrasound and could not be classified into the 2 subgroups (brain injury vs. no brain injury).
+
Preterm children with brain injury vs. no brain injury, p-value < 0.05 (Fisher's exact test)