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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Dev Biol. 2008 Sep 27;325(1):33–42. doi: 10.1016/j.ydbio.2008.09.021

Figure 7.

Figure 7

axJ mouse embryonic fibroblasts do not have altered growth rates or sensitivity to DNA damaging agents (A) 3T9 assay of mouse embryonic fibroblasts isolated from E14 wild type (wt) and axJ embryos. Cells were plated at a density of 9 × 105 cells per dish, allowed to grow for 3 days, harvested, counted and replated at the original density. Cell densities, indicated as population doublings, were recorded for the first 12 passages. (B) Sensitivities of mouse embryonic fibroblasts from E14 wild type (wt) and axJ embryos to the DNA damaging agent Mitomycin C. Cells were grown in the presence or absence of Mitomycin C for 24 h, and viability is presented as percent survival relative to wild type controls grown in the absence of Mitomycin C.