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. 2009 Mar 10;4(3):e4770. doi: 10.1371/journal.pone.0004770

Table 1. Nuclear morphology of striatal neurons.

Neuronal marker Category Nuclear diameter1 Nuclear shape2 TO-PRO-3 staining3
DARPP-32 A 10–11 µm Rounded ≥3 scattered clumps, sharp nuclear limit with thin discontinuous peripheral line
Parvalbumin B 9–11 µm Slightly elongated 1–2 central clumps
Calretinin C 6–10 µm Irregular rounded 1 central clump
Somatostatin D 8–12 µm Elliptic (axis ratio ≥1.5) 1 central clump
ChAT E 10–13 µm Irregular Irregular staining with one or more clumps of various sizes
1

Nuclear diameter is defined as the longest line that can cross the nucleus.

2

Nuclear shape is fixed by drawing the outline of the nucleus.

3

Refers to regions of intense TO-PRO-3 staining (clumps). The rest of the nucleus contains light staining.