Table 1. Induction of PPRE-Luciferase Activity by Derivatives of 2′-des-Methyl Sulindac Sulfide.
EC50 is the concentration of compound required to achieve 50% of the maximum induction of PPRE-luciferase activity. Means ± SD are shown, n = 3.
A 2-fold induction corresponds to a doubling of luciferase activity relative to vehicle-treated control.