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Kd values and kinetic parameters obtained for the oligonucleotides shown in Figure 1Bii
| X | Clustered |
Dispersed |
||
|---|---|---|---|---|
| Kd (µM) | k1 (µM min−1) | Kd (µM) | k1 (µM min−1) | |
| PdU | 0.5 ± 0.2 | – | 0.4 ± 0.2 | – |
| DMAPdU | 1.2 ± 0.2 | 0.020 ± 0.001 | 0.6 ± 0.3 | 0.026 ± 0.002 |
| APdU | 0.1 ± 0.02 | 0.042 ± 0.007 | 0.2 ± 0.02 | 0.034 ± 0.001 |
| GPdU | 0.2 ± 0.1 | – | 0.2 ± 0.1 | – |
Kd values were determined at pH 6.0, while k1 was determined at pH 5.0.
