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. 2008 Dec 18;37(4):1035–1048. doi: 10.1093/nar/gkn1004

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© 2008 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Biogenesis of microRNAs. Processing of both host miRNAs (violet) and virus-encoded miRNAs (blue) is assumed to occur through the same pathway. The arrows (pink) indicate the effects of cellular miRNAs on their own cellular transcripts as well as on viral transcripts. The violet arrow shows the effects of virus-encoded miRNAs on both cellular and viral transcripts. Both these arrows suggest possible miRNA-mediated interactions between viruses and their hosts.