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Competition dialysis metric results for the positive controls, MHQ-15, OZ-85H and the virtual screening top results, compounds 1 and 2
| Test ligand | Cb (μM) | Kapp/105 (M−1) | SS | Cmax/SS (μM) |
|---|---|---|---|---|
| MHQ-12a | 11.8 | 1.87 | 1.32 | 8.93 |
| MHQ-15 | 10.7 | 1.7 | 1.66 | 6.44 |
| OZ-85H | 17.6 | 3.1 | 3.69 | 4.77 |
| Compound 1 | 24.2 | 4.8 | 2.30 | 10.47 |
| Compound 2 | 30.0 | 6.7 | 1.92 | 15.63 |
aThese data are included from a previous publication (18).
