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. Author manuscript; available in PMC: 2009 Mar 5.
Published in final edited form as: Nat Biotechnol. 2008 Nov;26(11):1251–1259. doi: 10.1038/nbt.1499

Figure 3. Multiple activity motifs overlay the pentose phosphate pathway and glycerol biosynthesis.

Figure 3

(a–e) Shown are the PPP and glycerol synthesis pathway (GSP) (a), along with activity motifs identified in four different conditions (b–e). Names in rectangles denote catalyzing enzyme; red denotes activation, green denotes repression; values denote the time of activation or repression onset. (b) Forward activation of the PPP and backward activation and funnel-same-time-activation of the GSP in response to a heat shock. (c) Forward-activation of PPP and backward-shutoff of GSP in response to menadione. (d) Forward activation of PPP and backward activation of GSP in response to diamide. (e) Forward shutoff and funnel-same-time forward shutoff in response to de-heating.