Table 1. Comparison of the efficacy of carboxyfullerene isomers with other commonly studied antioxidants.

Mixed cortical cultures were exposed to NMDA for 10 min in the presence of antioxidant compounds, and cell death assessed at 24 h by LDH release. A range of concentrations for each antioxidant were tested; the maximal protection and the concentration at which it was achieved are listed. Values are expressed as % of NMDA-induced death in the absence of test compound.

Drug	IC50, µM	%Maximum achievable protection [µM]
C3lite	10	66 [10]
BisE	>100	43 [100]
P2	17	93 [100]
C3	4	100 [30]
E	9	87 [100]
D3	>100	46 [100]
α-tocopherol	>100	22 [100]
MnTMPyp	>100	16 [50]
Phenylbutyl nitrone	>100	15 [300]