Table 3.
Growth of virus in nonscarified eyes
| Virus | # Positive eyes/total tested
|
Mean* | Peak† | %Positive | ||
|---|---|---|---|---|---|---|
| 36 hpi | 60 hpi | 84 hpi | ||||
| HSV-1(F) | 2/6 | 1/6 | 2/4 | 1.2 | 1.4 | 31 |
| R6012 | 0/6 | 1/6 | 0/2 | 1.8 | 1.8 | 7‡ |
| R6016 | 3/6 | 1/6 | 2/2 | 2.3 | 2.5 | 43 |
| RAS104 | 0/6 | 0/6 | 1/2 | 1.7 | 1.7 | 7‡ |
| RAS105 | 3/6 | 3/6 | 2/2 | 2.0 | 2.0 | 57 |
| WT total | 8/18 | 6/18 | 6/8 | 1.8 | 44‡ | |
hpi, hours postinfection. WT, wild type.
Log geometric mean titer of virus in all eyes positive at all times indicated.
Log geometric mean titer of virus in all positive eyes at time of highest mean titer.
P < 0.05 comparing either R6012 or RAS104 to sum of wild-type viruses.