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. Author manuscript; available in PMC: 2009 Mar 5.
Published in final edited form as: Alcohol Clin Exp Res. 2008 Dec 13;33(3):419–427. doi: 10.1111/j.1530-0277.2008.00852.x

Fig. 5.

Fig. 5

Effects of exogenous IL-15 and combined IL-15 and IL-15Rα treatment on NK cell proliferation and apoptosis in water-drinking and alcohol-consuming mice. Groups containing 5 mice were given water or alcohol for 3 months and then treated with IL-15 alone or IL-15 combined with IL-15RαFc as described in Material and Methods. Values are mean ± SD. (A) Percentage of CD3-NK1.1+ cells in the spleens of treated mice. (B) Number of CD3-NK1.1+ cells in the spleen of treated mice. (C) Percentage of Annexin V+ CD3-NK1.1+ NK cells. (D) Percentage of BrdU+ CD3-NK1.1+ cells. IL-15Ra = IL-15Rα. White bars, water-drinking mice; hatched bars, alcohol-consuming mice. aDifferent from water group, p < 0.05. bDifferent from control and IL-15 treated groups but not from each other, p < 0.05. cDifferent from control and IL-15/IL-15Rα treated groups but not from each other, p < 0.05.