Table 2. Odds ratios for the joint and marginal effects of single nucleotide polymorphisms complement factor H 402 and rs11200638 on age-related macular degeneration.
rs11200638 |
|||
CFH 402 |
GG/GA |
AA |
CFH 402 risk (adjusted for rs11200638) |
TT |
1 |
7.92 |
1 |
CT |
1.11 |
30.52 |
1.41 (95% CI: 0.54,3.74) |
rs11200638 risk adjusted for CFH | 1 | 10.02; 95% CI: 4.36,23.06 |
CFH indicates complement factor H. Joint odds ratios were calculated from standard formulae. Marginal odds ratios and 95% confidence intervals were calculated using logistic regression (see Methods) with each SNP was adjusted for the other.