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. 2009 Mar 10;4(3):e4775. doi: 10.1371/journal.pone.0004775

Figure 2.

Figure 2

(a) Brain metastasis of a melanoma lacking MGMT immunoreactivity. MGMT-immunopositive endothelial cells and leukocytes served as internal positive control (arrow). (b) Heterogeneous MGMT immunoreactivity revealing MGMT-positive tumor cells intermingled with MGMT negative tumor cells (breast carcinoma). (c) Strong nuclear reaction for MGMT in all tumor cells (lung carcinoma). Scale bar: a–c: 100 µm.