Table 3. Comparison of red cell phospholipid fatty acid composition in healthy subjects and patients with cystic fibrosis (CF).
Phospholipid fatty acids | Controls | CF patients | p-value | |
PE | SFA | 61,1 (60,6–61,8) | 67,8 (52,2–69,0) | 0,317 |
MUFA | 18,6 (18,2–19,8) | 27,2 (26,0–33,5) | 0,019 | |
PUFA | 19,6 (18,2–20,7) | 5,1 (3,4–9,9) | 0,002 | |
UFA | 38,9 (38,2–39,4) | 33,2 (31,0–47,8) | 0,317 | |
W3 | 1,1 (1,1–1,4) | 0,5 (0,4–0,6) | 0,019 | |
W6 | 18,2 (17,1–19,3) | 4,6 (3,1–8,4) | 0,002 | |
PC | SFA | 60,7 (58,1–60,8) | 74,3 (67,5–78,1) | 0,002 |
MUFA | 24,1 (23,8–24,5) | 18,4 (16,6–24,3) | 0,125 | |
PUFA | 16,2 (15,3–19,5) | 7,6 (4,0–8,3) | 0,002 | |
UFA | 39,3 (39,2–41,9) | 25,7 (21,9–32,5) | 0,002 | |
W3 | <0,01 (<0,01–<0,01) | 0,4 (0,3–0,5) | 0,002 | |
W6 | 16,2 (15,3–19,5) | 7,3 (3,5–8,1) | 0,002 |
PE: phosphatidylethanolamine; PC: phosphatidylcholine; SFA: saturated fatty acids, MUFA: monounsaturated fatty acids, PUFA: polyunsaturated fatty acids; UFA: unsaturated fatty acids; W3: n-3 fatty acids; W6: n-6 fatty acids. Data are summarized as medians and interquantile ranges.