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. 2009 Mar 11;4(3):e4802. doi: 10.1371/journal.pone.0004802

Table 1. Demographics of the research participants.

Characteristics Healthy females Healthy males p Diseased females Diseased males p
(n = 10) (n = 9) (n = 14) (n = 9)
Age (years) 54.3±13.2 55.3±17.5 0.9 51.0±18.5 49.0±31.3 0.85
Ethnicity
Asian Pacific Islander 0 0 2 0
White, non-Hispanic 1 2 1 0
Black, non-Hispanic 5 5 4 3
Hispanic 0 1 2 1
Other & Unknown 4 1 5 5
Weight, (kg) 77.8±18.0 76.3±16.8 0.86 84.1±26.8 72.0±26.0 0.35
BMI (kg/m2) 26.9±5.0 23.2±4.0 0.14 32.4±10.6 26.0±7.3 0.16
HTN 1 (10%) 5 (55.6%) 0.06 8 (57.1%) 4 (44.4%) 0.68
DM 0 0 8 (57.1%) 5 (55.6%)
Proteinuria (dipstick)
Negative 7 7 5 1
30 mg/dL 2 1 1 4
100 mg/dL 0 0 4 3
Unknown 1 1 4 1
Serum BUN (mg/dL) 13.7±3.5 15.1±4.0 0.43 21.5±15.8 22.0±17.7 0.91
Serum creatinine (mg/dL) 1.0±0.3 1.2±0.3 0.06 2.2±2.3 1.0±1.1 0.38
eGFR (ml/min) 78.0±32.7 77.9±16.5 0.99 57.6±47.0 78.0±56.8 0.4
Histology
Normal 10 9 0 0
Diabetic Nephropathy 5 0
FSGS 2 6
Arteriosclerosis 1 0
Global glomerulosclerosis 4 0
Fibrosis 1 2
Unknown 1 1

Abbreviations used: BMI: Body Mass Index; DM: Diabetes Mellitus; BUN: Blood Urea Nitrogen; FSGS, Focal Segmental Glomerulosclerosis. eGFR (estimated glomerular filtration rate) was calculated using the MDRD formula. Student's t-test was used to determine the statistical significance between sexes for age, weight, BMI, BUN, creatinine, eGFR.