Table 1.
Patient's Condition | Reference | First-Degree Relative's Risk
|
|||||||
---|---|---|---|---|---|---|---|---|---|
Chronic Lymphocytic Leukemia
|
Hodgkin's Lymphoma
|
Non-Hodgkin's Lymphoma
|
Multiple Myeloma
|
||||||
OR | 95% CI | OR | 95% CI | OR | 95% CI | OR | 95% CI | ||
Chronic lymphocytic leukemia | Goldin et al5 | 7.5 | 3.6 to 15.6 | 2.4 | 1.1 to 5.1 | 1.5 | 1.0 to 2.2 | 1.1 | 0.5 to 2.4 |
Hodgkin's lymphoma | Goldin et al21 | 2.1 | 1.2 to 3.8 | 3.1 | 1.8 to 5.3 | 1.3 | 0.9 to 1.8 | 1.0 | 0.6 to 1.8 |
Non-Hodgkin's lymphoma | Goldin et al27 | 1.3 | 0.9 to 1.9 | 1.4 | 1.0 to 2.0 | 1.7 | 1.4 to 2.2 | 1.1 | 0.8 to 1.5 |
Multiple myeloma | Landgren et al50 | 0.9 | 0.4 to 1.9 | 0.7 | 0.4 to 1.5 | 1.2 | 0.8 to 1.7 | 1.7 | 1.0 to 2.7 |
NOTE. Italic font indicates not significant. Bold font indicates increased risk P < .05. Table constructed using odds ratios and 95% CIs for the risk of lymphoproliferative malignancy in relatives of patients diagnosed in Sweden and Denmark with chronic lymphocytic leukemia, Hodgkin's lymphoma, non-Hodgkin's lymphoma, and multiple myeloma as reported in the respective publications.