Table A2.
IFN-γ Release (pg/mL) From TIL Demonstrating Specificity for Autologous Melanoma Cell Lines With Unknown Peptide Antigen Specificity
| Cells | Allogeneic Melanoma Cell Line
|
Autologous Melanoma Cell Line
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| None | 888 | 938 | 526 | 624 | SB-1 | SB-2 | SB-9 | SB-11 | SB-18 | SB-23 | |
| HLA-A loci | 01 24 | 02 24 | 02 03 | 02 03 | 02 68 | 02 03 | 23 31 | 01 26 | 03 24 | 01 02 | |
| Patient TIL | |||||||||||
| 1 | 19 | 5 | 5 | 10 | 5 | 1,276 | |||||
| 2 | 0 | 0 | 0 | 98 | 38 | 3,310 | |||||
| 9 | 12 | 0 | 82 | 2 | 4 | 232 | |||||
| 11 | 6 | 4 | 14 | 7 | 5 | 11,850 | |||||
| 18 | 3 | 31 | 15 | 5 | 1 | 305 | |||||
| 23 | 0 | 14 | 12 | 0 | 3 | 1,435 | |||||
NOTE. Values shown in bold are at greater than twice background and greater than 200 pg/mL.
Abbreviation: TIL, tumor-infiltrating lymphocytes.